WORLD’S BEST SOUP – OR WHAT ARE THE BENEFITS OF SALVESTROL – A NATURAL PROTECTION AGAINST CANCER
Salvestrol (from lat. Salvus – whole, safe) is a substance produced by some plants as a protective reaction against fungi, viruses, bacteria or insects. It is mainly found in the peel of fruits, in the seeds, leaves and outer shells of root crops.
HOW ARE THESE SUBSTANCES GOOD FOR US?
The fact is that British researchers Gerard Potter and Dan Burke, who were developing a safe method for cancer treatment, found that an enzyme called CYP1B1 is an internal component of cancer cells and is present in a wide range of different types of cancer that have been studied to date, but is missing in normal cells.
In subsequent experiments, it was found that salvestrols are activated (converted into metabolites) inside human cancer cells by this CYP1B1 enzyme and cause cancer cells to stop growing or even cause cancer cell death without harming normal cells.
Therefore, Salvestrols are a new class of natural anti-cancer elements that are contained in plants and can be included in our daily diet easily.
It is important to know that our (even healthy) organism constantly produces cancer cells, and statistics show that approximately 4 out of 10 men and 3.5 out of 10 women will have cancer during their lifetime.
Since salvestrol helps the body get rid of them, they are the best prevention against cancer.
WHERE DO WE GET SALVESTROL FROM?
Our body itself does not synthesize salvestrol, they enter the body through nutrition. Important sources of salvestrols are:
Vegetables: leafy vegetables (celery spinach etc), whole cabbage, bell pepper, wild carrots, artichoke, asparagus, watercress, rocket salad, avocado, bean sprouts, sprouted soybeans, celery, cucumber, pumpkin, zucchini, eggplant, olives, garlic, onions …
Fruits: red fruits, blueberries, currants, grapes, apples, strawberries, plums, figs, raspberries, tangerines, oranges, blueberries, pears, melons, pineapple, mango, chokeberry …
Herbs and teas: parsley, basil, rosemary, thyme, sage, mint, dandelion, rooibos, plantain, dogrose, milk thistle, hawthorn berries, chamomile, dill, burdock, lemon verbena …
WORLD’S BEST SOUP?
Salvestrols are heat-resistant, but when vegetables are cooked, salvestrols “go” into the water in which you cook vegetables. If you only cook and eat vegetables, salvestrols do not enter your body. But the soup is good precisely because of what we eat and the broth / broth, in which everything is the same!
In Eastern European kitchen, perhaps the most popular soup is „borsch“! And for a reason so! Indeed, almost all vegetables in its composition contain
salvestrol (cabbage, onions, carrots, peppers, parsley … :))
HOW TO GET ENOUGH SALVESTROL?
Unfortunately, the majority of the population has a serious deficit of salvestrol (more on the reasons below), thereby predisposing us to cancer.
The source of salvestrol for us are:
- eating unprocessed, organically grown vegetables, fruits and herbs
- extracts of organically grown vegetables or fruits in the form of food supplements
WHY “ORGANICALLY GROWN” IS SO IMPORTANT?
This is due to the fact that plants that grow in a more natural environment are constantly exposed to pathogenic factors, and thus have an incentive to produce salvestrol with the simple goal of self-defense. Due to the use of various pesticides and fungicides, the content of salvestrol in non-organically grown plants is significantly less (up to 30 times!).
DO ALL PRODUCTS CONTAIN SALVESTROL?
Today, our food contains 80-90% less salvestrol than 100 years ago. Why is that?
Salvestrols are mainly found in the peel, but in a modern diet this part of fruits or vegetables is the least attractive for us and is often not eaten.
An average statistical vegetable or fruit in a store was grown using pesticides.
We have become very picky to the look and taste of food, therefore, to sell us more, food manufacturers remove salvestrol to enhance taste, color and “purity” of food. The fact is that salvestrol is tastes somehwat bitter (remember cabbage, raddish, good olive oil, etc.). To get a tasty (read sweetish) product without the need for sugar, producers need to remove salvestrol or bring out a new variety of plants – less bitter, but, unfortunately, less healthy.
Refined foods usually contain very little or no salvestrol at all.
EVEN WINE IS SUBJECT TO THIS
The traditional method of making wine is the fermentation of grape juice with skins. Wine produced in such way contains a lot of salvestrol (20 mg of reservatrol per bottle of wine). This is because salvestrol is contained in the skin of grapes. Today, the technology of winemaking has been simplified, and winemakers often ferment wine without skins. Therefore, salvestrol in such wine is ten times (2 mg / bottle) less than in traditionally made wine, and therefore conversaion of usefullness of red wine stops right here.
Scientists believe that a decrease in protective salvestrols and an increase in carcinogens in food may have contributed to the growth of cancer in recent decades.
HOW MUCH SALVESTROL DO WE NEED?
If our daily diet consists of 5 meals, which includes a lot of vegetables and fruits, then we get about 20 points of salvestrol in this way. If these are organically grown products – then 60-70.
The minimum daily dose recommended for maintaining health is estimated by specialists at 100 points of salvestrol. Additional protection is achieved by 350 points, and therapeutic recovery requires large daily doses of 2×2000 points. Of course all of this is individual, and treatment should be agreed with specialists.
Dr. Natalia Trofimova ja Liina Molenaars
LITERATURE
Brian A Schaefer Salvestrol. Natural defense against cancer, 2012.
Holford, L.Efiong Say no to cancer, 2010
Brian A Schaefer Salvestrols. Journeys to wellness, 2013.
The Role of Salvestrols in the Managemenе of Cancer Paеents at the Schachter Center in New York Michael B Schachter MD, CNS Schachter Center for Complementary Medicine, Orthomolecular Medicine Today Conference Vancouver BC CAI March 25, 2014
McFadyen MC, Melvin WT, Murray GI. Cytochrome P450 enzymes: novel options for cancer therapeutics. Mol Cancer Ther 2004;3:363–71.
Murray GI, Taylor MC, McFadyen MC et al. Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res 1997;57(14):3026-31
www.orthokennis.nl/artikelen/bitter-is-better-an-introduction-to-salvestrols
Tokizane T, Shiina H, Igawa M et al. Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer. Clin Cancer Res 2005;11(16):5793-801.
Gribben JG, Ryan DP, Boyajian R et al. Unexpected association between induction of immunity to the universal tumor antigen CYP1B1 and response to next therapy. Clin Cancer Res 2005;11(12):4430-6.
Murray GI, Melvin WT, Greenlee WF, Burke MD. Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1. Annu Rev Pharmacol Toxicol. 2001;41:297-316.
Doostdar H, Burke MD, Mayer RT. Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1. Toxicology. 2000;144(1-3):31-8.
Gibson P, Gill JH, Khan PA et al. Cytochrome P450 1B1 (CYP1B1) is overexpressed in human colon adenocarcinomas relative to normal colon: implications for drug development. Mol Cancer Ther. 2003;2(6):527-34.
Sale S, Tunstall RG, Ruparelia KC et al. Effects of the potential chemopreventive agent DMU-135 on adenoma development in the ApcMin+ mouse. Invest New Drugs 2006;24(6):459-64.
Potter GA, Patterson LH, Wanogho E et al. The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1. Br J Cancer 2002;86(5):774-8.
Jang M, Cai L, Udeani GO et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997;275(5297):218-20.
Remsberg CM, Yanez JA, Ohgami Y et al. Pharmacometrics of pterostilbene: preclinical pharmacokinetics and metabolism, anticancer, antiinflammatory, antioxidant and analgesic activity. Phytother Res. 2007 Aug 29; DOI: 10.1002/ptr.2277.
Vitrac X, Bornet A, Vanderlinde R et al. Determination of stilbenes (delta-viniferin, trans-astringin, trans-piceid, cis- and transresveratrol, epsilon-viniferin) in Brazilian wines. J Agric Food Chem. 2005;53(14):5664-9.
Mikstacka R, Przybylska D, Rimando AM et al. Inhibition of human recombinant cytochromes P450 CYP1A1 and CYP1B1 by transresveratrol methyl ethers. Mol Nutr Food Res. 2007;51(5):517-24.
Potter GA, Burke MD. Salvestrols – natural products with tumour selective activity. Journal of Orthomol. Medicine 2006;21(1):34- 36.
www.salvestrolen.nl
McFadyen MC, Murray GI. Cytochrome P450 1B1: a novel anticancer therapeutic target. Future Oncol. 2005;1(2):259-63. 17. McFadyen MC, McLeod HL, Jackson FC et al. Cytochrome P450 CYP1B1 protein expression: a novel mechanism of anticancer drug resistance. Biochem Pharmacol. 2001;62(2):207-12.